Case Report on Capillary Hemangioma of the Maxillofacial Region
DOI:
https://doi.org/10.48165/ajm.2026.9.01.15Keywords:
Capillary Hemangioma, Vascular Tumor, Maxillofacial Swelling, ISSVA classification, Surgical Excision, Immunohistochemistry, MRI, Psychosocial ImpactAbstract
Capillary hemangiomas are benign vascular proliferations that commonly present in childhood but can persist or appear in adulthood. This case report discusses a rare presentation of an extensive capillary hemangioma involving the maxillofacial region. The patient presented with progressive swelling over three months, with significant facial asymmetry. Diagnosis was confirmed through clinical, radiological, and histopathological examination. The lesion was surgically excised, with post-operative recovery documented. This case highlights the clinical presentation, diagnostic approach, and surgical management of capillary hemangiomas in the maxillofacial region. A comprehensive discussion is included to explore the histopathological features, pathogenesis, differential diagnoses, psychosocial considerations, and therapeutic approaches including current advancements and consensus guidelines.References
Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69(3):412-22. doi:10.1097/00006534-198203000-00002.
Enjolras O, Riche MC, Merland JJ, Escande JP. Management of alarming hemangiomas in infancy: a review of 25 cases. Pediatrics. 1990;85(4):491-8. doi:10.1542/peds.85.4.491.
Blei F, Walter JW. Histopathologic and clinical features of vascular anomalies. Otolaryngol Clin North Am. 2002;35(6):1187-1201.
Léauté-Labrèze C, Dumas de la Roque E, Hubiche T, Boralevi F, Thambo JB, Taïeb A. Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008;358(24):2649-51. doi:10.1056/NEJMc0708819.
Greene AK, Rogers GF, Mulliken JB. Involuting hemangioma: implications for surgical intervention. Plast Reconstr Surg. 2004;113(7):1945-52.
International Society for the Study of Vascular Anomalies (ISSVA). ISSVA classification for vascular anomalies. 2020. Available from: https://www.issva.org/classification
Boon LM, Enjolras O, Mulliken JB. Congenital hemangioma: evidence of accelerated involution. J Pediatr. 1996;128(3):329-35.
North PE, Waner M, James CA, Mizeracki A, Frieden IJ, Mihm MC Jr. GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. Hum Pathol. 2000;31(1):11-22.
Jacob AG, Driscoll DJ, Shaughnessy WJ, Stanson AW, Clay RP, Gloviczki P. Symptomatic hemangiomas and vascular malformations in the adult: a 15-year experience with 133 patients. Mayo Clin Proc. 1998;73(6):590-5.
Chen TS, Eichenfield LF, Friedlander SF. Infantile hemangiomas: an update on pathogenesis and therapy. Pediatrics. 2013;131(1):99-108.
Baselga E, Roe E, Coulie J, et al. Risk stratification of infantile hemangiomas. J Am Acad Dermatol. 2016;74(3):593-605.
Amaral J, Taddio A, Bauman M. Topical and systemic treatments for infantile hemangiomas: current and future perspectives. Pediatr Drugs. 2017;19(2):125-35.
Mazereeuw-Hautier J, Syed S, Harper J. Management of difficult hemangiomas. Clin Dermatol. 2005;23(6):596-608.
Casanova D, Boon LM, Vikkula M. Vascular anomalies: from genetics toward models for therapeutic trials. Cold Spring Harb Perspect Med. 2020;10(11):a036210. doi:10.1101/cshperspect.a036210.
Chiller KG, Passaro D, Frieden IJ. Hemangiomas of infancy: clinical characteristics, morphologic subtypes, and their relationship to race, ethnicity, and sex. Arch Dermatol. 2002;138(12):1567-76.

