A Study of Clinical and Etiological Profile of Anaemia in Geriatric Patients in a Tertiary Care Hospital

Authors

  • R P Buden M.D. Gen Medicine, Assistant Professor , Dept of Gen Medicine, SSIMS Medical College , T Begur NelamangalaTq, Bengaluru Rural Dist.

DOI:

https://doi.org/10.48165/z2yvm133

Keywords:

Anemia, elderly, geriatrics

Abstract

Background: Geriatric anemia is a global health problem because of its high prevalence and associated significant morbidity and mortality. Aim: The objectives of this study were to estimate the pattern of anemia in the elderly patients and the underlying etiology of anemia. Subjects  and Methods: This was a hospital-based prospective observational study, conducted in patients aged 60 years and above at SSIMS, T. Begur.  Anemia is defined as hemoglobin level less than 13 g/dl in men and 12 g/dl in women. Results: Among the 100 older patients with anemia, the  mean value of hemoglobin was 8.9 ± 2.3 g/dl. The etiological distribution of anemia was iron deficiency in 25 patients (25%), chronic disease  in 22 patients (22%), hematological disorders in 20 (20%), chronic kidney disease in 12 (12%), multifactorial in 8 (8%), vitamin B12  deficiency in 3 (3%), folate deficiency in 1 (1%), and hypothyroidism in 1 patient (1%). No etiology could be found in 8 patients (8%). 57.6%  of the iron-deficient patients had upper gastrointestinal lesions and 30.7% had a nutritional cause. Common chronic diseases causing anemia  were malignancy (36.6%) and liver disease (29.1%). The myelodysplastic syndrome was the commonest hematological disorder. 53.35% of the  patients had normocytic anemia, 40% had microcytic anemia, and 6.6% had macrocytic anemia. Conclusion: In most of the cases, anemia in  the elderly had a treatable cause. Thus, a thorough investigation including gastrointestinal endoscopy is warranted. Unexplained progressive or  unresponsive anemia requires bone marrow examination. 

References

1. Stauder R, Valent P, Theurl I. Anemia at older age: Etiologies, clinical implications, and management. Blood.2018;131:505–14.

2. Halawi R, Moukhadder H, Taher A. Anemia in the elderly: A consequence of aging? Expert Rev Hematol. 2017;10:327–35. 3. S. D. Denny, M. N. Kuchibhatla, and H. J. Cohen, “Impact of anemia on mortality, cognition, and function in community-dwelling elderly,” American Journal of Medicine, vol. 119, no. 4, pp. 327–334, 2006. 4. BeghéC, Wilson A, Ershler WB. Prevalence and outcomes of anemia in geriatrics: A systematic review of the literature. Am J Med.

2004;116(Suppl 7A):3S–10S.

5. Penninx BW, Guralnik JM, Onder G, Ferrucci L, Wallace RB, Pahor M. Anemia and decline in physical performance among older persons. Am J Med. 2003;115:104–10.

6. Chaves PH, Semba RD, Leng SX, Woodman RC, Ferrucci L, Guralnik JM, et al. Impact of anemia and cardiovascular disease on frailty status of community-dwelling older women: The women's health and aging studies I and II. J Gerontol A BiolSci Med Sci. 2005;60:729–35.

7. Atti AR, Palmer K, Volpato S, Zuliani G, Winblad B, Fratiglioni L. Anaemia increases the risk of dementia in cognitively intact elderly. Neurobiol Aging. 2006;27:278–84.

8. Onder G, Penninx BW, Cesari M, Bandinelli S, Lauretani F, Bartali B, et al. Anemia is associated with depression in older adults: Results from the InCHIANTI study. J Gerontol A BiolSci Med Sci. 2005;60:1168–72.

9. Chaves PH, Ashar B, Guralnik JM, Fried LP. Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women: Should the criteria currently used to define anemia in older people be reevaluated? J Am Geriatr Soc. 2002;50:1257–64.

10. 10. Dharmarajan TS, Norkus EP. Mild anemia and the risk of falls in older adults from nursing homes and the community.J Am Med Dir Assoc.2004;5:395–400.

Downloads

Published

2019-11-30

How to Cite

A Study of Clinical and Etiological Profile of Anaemia in Geriatric Patients in a Tertiary Care Hospital . (2019). Academia Journal of Medicine, 2(2), 114–117. https://doi.org/10.48165/z2yvm133