Clinical Profile of Idiopathic Pulmonary Fibrosis
DOI:
https://doi.org/10.48165/n8s60j16Keywords:
Idiopathic Pulmonary Fibrosis, Interstitial Lung Diseases, DyspneaAbstract
Background: The incidence of IPF was estimated at 10.7 cases per 100,000 per year for men and 7.4 cases per 100,000 per year for women in a population-based study from the county of Bernalillo, New Mexico. A study from the United Kingdom reported an overall incidence rate of only 4.6 per 100,000 person-years, but estimated that the incidence of IPF increased by 11% annually between 1991 and 2003. This increase was not felt to be attributable to the aging of the population or increased ascertainment of milder cases. Subjects and Methods: This was an observational prospective study carried out in the Department of Pulmonary Medicine, Medical College. The study included 35 patients diagnosed with IPF during the two year study period. Results: Dyspnea was the most common symptom at presentation, being present in 35 (100 %) of the patients. Cough with or without expectoration was the next most common symptom, being present in 33 (94.2 %) of the patients. Other symptoms were chest pain, fever and weight loss, and joint pains. Conclusion: Clinical prediction models are used in many areas of medicine to provide accurate prognostic information and staging of disease; such a prediction model would be useful in IPF.
References
1. Nathan SD. Lung transplantation: disease-specific considerations for referral. Chest. 2005;127:1006-16.
2. Trulock EP, Edwards LB, Taylor DO, Boucek MM, Keck BM, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult lung and heartlung transplantation report -2006. J Heart Lung Transplant. 2006;25:880- 92.
3. Michael A. Nead, David G. Morris. Interstitial lung disease: a clinical overview and general approach. In: Fishman’s pulmonary diseases and disorders, 4th ed. McGraw Hill 2008;1:1103-24.
4. Hamman, L., and A. Rich. Acute diffuse interstitial fibrosis of the lung. Bull. Johns Hopkins Hosp .1944;74:177-12.
5. Liebow, A. A. Definition and classification of interstitial pneumonias in human pathology. Prog. Respir. Res.1975;8:1-31.
6. Anna-luise a. katzenstein and jeffrey l. myers Idiopathic Pulmonary Fibrosis Clinical Relevance of Pathologic Classification Am J RespirCrit Care Med; 1998 Vol 157. pp 1301-15.
7. Maheshwari U, Gupta D, Aggarwal A.N, Jindal S.K. Spectrum and diagnosis of Idiopathic pulmonary fibrosis. Indian T.Chestdis Allied Sci. 2004; 46: 23-26.
8. Rasul S, Khalid M.C, Imran N, Khan S.U, Younus M. Gender Differences in Clinical Presentation of Idiopathic Pulmonary Fibrosis at Lahore, Pakistan. Annals 2010; 16: 286-89.
9. Cherniack, R. M., T. V. Colby, A. Flint, W. M. Thurlbeck, J. A. Waldron, Jr., L. Ackerson, M. I. Schwarz, and T. E. King, Jr. Correlation of structure and function in idiopathic pulmonary fibrosis. Am.J. Respir. Crit. Care Med.1995;151:1180–88.
10. Bjoraker, J. A., J. H. Ryu, M. K. Edwin, J. L. Myers, H. D. Tazelaar, D. R. Schroeder, and K. P. Offord. Prognostic significance of histopathological subsets in idiopathic pulmonary fibrosis. Am. J. Respir.Crit. Care Med.1998;157:199-203.
11. Katzenstein, A.-L. A., J. L. Myers, W. D. Prophet, L. S. Corley, III, and M. S. Shin. Bronchiolitis obliterans and usual interstitial pneumonia: a comparative clinicopathologic study. Am. J. Surg. Pathol. 1986;106: 373-81.
12. Guerry-Force, M. L., N. L. Muller, J. L. Wright, B. Wiggs, C. Coppin, P. D. Pare, and J. C. Hogg.A comparison of bronchiolitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airways disease. Am. Rev. Respir. Dis.1987;135:705-12.
