TRIPOLAR ELECTRICAL STIMULATION AS A POTENTIAL MODULATOR OF METABOLIC AND HEMATOLOGICAL PROFILES IN MICE
DOI:
https://doi.org/10.48165/abr.2026.28.01.14Keywords:
Frequency, glucose, mice, tripolar, voltageAbstract
Elevated blood cholesterol and glucose levels are common conditions among the elderly, often requiring continuous pharmacological intervention. To explore alternative approaches, the present study investigated the effects of alternating electrical simulation on these parameters, as well as on hemoglobin concentration and blood viscosity, using mice as experimental subjects. Treatment were applied at voltages ranging from 0 to 2.0 V, with a frequency of 500 kHz, for durations of 3 or 5 min day-1 over a 5-day period. The results revealed that electric stimulation at 2.0 V for 5 min reduced cholesterol levels by 7.53-9.0% and glucose levels by 28.41%, while hemoglobin levels tended to increase without a consistent pattern. Blood viscosity decreased under stimulation at 1.0 and 1.5 V but increased at 2.0 V, indicating a voltage dependent response. In conclusion, electrical stimulation effectively lowered cholesterol and glucose levels in mice; however, its effects on hemoglobin and blood viscosity were non-linear, thus suggesting the need for further studies to optimize treatment parameters.Downloads
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