Aldosterone Assay To Evaluate Oxidative Stress In Marwari Lambs During Extreme Hot Ambience

Authors

  • Ashish Joshi Department of Veterinary Physiology, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner-334 001, Rajasthan (India)
  • Nalini Kataria Department of Veterinary Physiology, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner-334 001, Rajasthan (India)

DOI:

https://doi.org/10.48165/

Keywords:

Aldosterone, electrolytes, hot ambience, Marwari lambs, oxidative stress

Abstract

A study was undertaken to assess the function of aldosterone as oxidative  stress marker in lambs of Marwari breed during extreme hot ambience.Radio immunometric assay was used to determine serum aldosterone.  Results revealed significant (p0.05) increase in serum aldosterone, γ glutamyl transferase (GGT), sodium and chloride contents during hot  ambience as compared to moderate ambience. Serum potassium, calcium,  phosphorus and magnesium showed reverse trend and the values were  significantly lower during hot ambience as compared to moderate ambience.  Maximum per cent change was observed in serum GGT, thus establishing  the oxidative stress. A relationship of aldosterone with oxidative stress was  observed. Results visibly validated that besides diseases, ambient stress can  put in variations in aldosterone with the establishment of oxidative stress.  

Downloads

Download data is not yet available.

References

Banday, A.A. and Lokhandwala, M.F. 2011. Oxidative stress causes renal angiotensin II type 1 receptor upregulation, Na/H exchanger overstimulation and hypertension. Hypertension, 57: 452-459.

Brookes, P.S., Yoon, Y., Robotham, J.L., Anders, M.W. and Sheu, S.S. 2004. Calcium, ATP and ROS: A mitochondrial love-hate triangle. American Journal of Physiology, Cell Physiology, 287: C817–C833.

Calò, L.A., Zaghetto, F. and Pagnin, E. 2004. Effect of aldosterone and glycyrrhetinic acid on the protein expression of PAI-1 and p22phox in human mononuclear leukocytes. Journal of Clinical Endocrinology and Metabolism, 89: 1973-1976.

Chhokar, V.S., Sun, Y., Bhattacharya, S.K., Ahokas, R.A., Myers, L.K., Xing, Z., Smith, R.A., Gerling, I.C. and Weber, K.T. 2005. Hyperparathyroidism and the calcium paradox of aldosteronism. Circulation, 111: 871-878.

Horton, R. and Biglieri, E.G. 1962. Effect of aldosterone on the metabolism of magnesium. Journal of Clinical Endocrinology and Metabolism, 22: 1187-1190.

Kaps, M. and Lamberson, W.R. 2004. Biostatistics for Animal Science. CABI Publishing, Oxford, UK.

Kataria, N. and Kataria, A.K. 2006. Endocrine and metabolic responses of Marwari sheep in arid tract. Slovenian Veterinary Research, 43: 135-142.

Kataria, N., Kataria, A. K., Pandey, N., Maan, R., Joshi, A., Sankhala, L.N., Chaturvedi, M., Pachaury, R. and Pilania, P.K. 2012. Use of serum magnesium as a biomarker of oxidative stress in Marwari goat from arid tracts in India. Veterinary Research, 5: 91-96.

Kataria, N. and Kataria, A.K.2012. Use of serum gamma glutamyl transferase as a biomarker of stress and metabolic dysfunctions in Rathi cattle of arid tract in India. Journal of Stress Physiology and Biochemistry, 8(3): 23-29.

Kataria, N., Kataria, A.K., Agarwal, V.K., Garg, S.L. and Sahani, M.S. 2002. Effect of long term dehydration on serum constituents in extreme climatic conditions in camel (Camelus dromedarius). Indian Journal of Physiology and Pharmacology, 46: 218-222.

Aldosterone assay to evaluate oxidative stress 199

Kataria, N., Kataria, A.K., Agarwal, V.K., Garg, S.L., Sahani, M.S. and Singh, R. 2000. Effect of water restriction on serum aldosterone and cortisol in dromedary camel during winter and summer. Journal of Camel Practice and Research, 7:1-7.

Kataria, N. and Kataria, A.K. 2013. Ambience associated variation in serum biomarkers of oxidative stress in donkeys of arid tracts in India. Egyptian Journal of Biology, 15: 21-24. Kataria, N. and Kataria, A.K. 2007. Compartmental water management of Marwari sheep during dehydration and rehydration. Veterinarski Arhiv, 77: 551-559.

Kotlyar, E., Vita, J.A., Winter, M.R., Awtry, E.H., Siwik, D.A., Keaney, J.F. Jr., Sawyer, D.B., Cupples, L.A., Colucci, W.S. and Sam, F. 2006. The relationship between aldosterone, oxidative stress and inflammation in chronic, stable human heart failure. Journal of Cardiac Failure, 12: 122-127.

Lee, D.H., Blomhoff, R. and Jacobs, D.R. Jr. 2004. Is serum gamma glutamyltransferase a marker of oxidative stress? Free Radical Research, 38: 535-539.

Nishiyama, A., Kusaka, T. and Kitajima, H. 2007. Role of aldosterone in oxidative stress and renal injury. Yakugaku Zasshi, 127: 1331-1337.

Ojeda-Cervantes, M., Barrera-Chimal, J., Alberú, J., Pérez-Villalva, R., Morales-Buenrostro, L.E. and Bobadilla, N.A. 2013. Mineralocorticoid receptor blockade reduced oxidative stress in renal transplant recipients: A double-blind randomized pilot study. American Journal of Nephrology, 37: 481-490.

Oser, B.L. 1976. Blood analysis. pp. 975-1152. In: Hawk’s Physiological Chemistry (14th edn.), Tata McGraw, New Delhi, India.

Shebaita, M.K. and Pfau, A.1983. Changes in the electrolytes of serum and urine with heat exposure in the bovine. Beitrage zur Tropischen Landwirtschaft und Veterinarmediziz, 21: 445-451.

Varley, H. 1988. Tests in liver and biliary tract disease. pp. 158-467. In: Practical Clinical Biochemistry (4th edn.), CBS Publishers, New Delhi, India.

Walwadkar, S.D., Suryakar, A.N., Katkam, R.V., Kumbar, K.M. and Ankush, R.D. 2006. Oxidative stress and calcium-phosphorus levels in rheumatoid arthritis. Indian Journal of Clinical Biochemistry, 21: 134-137.

Wolf, P.L. and Williams, D. 1973. Practical Clinical Enzymology. Wiley-Interscience, New York, USA.

Published

2015-06-03

How to Cite

Aldosterone Assay To Evaluate Oxidative Stress In Marwari Lambs During Extreme Hot Ambience . (2015). Applied Biological Research, 17(2), 195–199. https://doi.org/10.48165/