Rare Case Of Parathyroid Adenoma In 22 Years Old Female Patient

Indian Journal of Applied Basic Medical Sciences
Year: 2021, Volume: 23(B), Issue. (2)
First page: (227) Last page: (231)
Online ISSN: 2249-7935
Print ISSN: 0975-8917
doi: 10.48165/ijabms.2021.233712 

Rare Case Of Parathyroid Adenoma In 22 Years Old  Female Patient
Dr. Charmi H. Savalia1, Dr. Minesh B. Gandhi2,Dr. Cherry K. Shah3
12nd Year Resident Department of Pathology,  Smt. N.H.L. Municipal Medical College, Ahmedabad.
2Associate Professor, Department of Pathology,  Smt. N.H.L. Municipal Medical College, Ahmedabad.
3Professor and Head of Department of Pathology,  Smt. N.H.L. Municipal Medical College, Ahmedabad.
Corresponding Author: Charmi H. Savalia, Email:

Online Published on 25-August-2021

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ABSTRACT

Background: Parathyroid adenoma is a benign tumour of parathyroid gland and most common cause of primary  hyperparathyroidism. Most common age group affected is 5-6th decade. Parathyroid adenoma  causes elevated level of parathormone hormone and serum calcium.  Method: A retrospective study was done in a case of 22 years old female having pathological fracture and  on examination found to have neck mass and was diagnosed as parathyroid adenoma of left inferior  gland with bone pathology. Patient undergone left inferior parathyroidectomy ,specimen was sent  to histopathology department and HPE confirmed the diagnosis of parathyroid adenoma. Patient  was followed up and did well after surgery. Observation: Parathyroid adenoma most commonly present as solitary gland enlargement and most common in  the inferior parathyroid glands (75%) followed by superior parathyroid glands (15%) and  anomalous position (10%). Of the latter 70% are in mediastinum and rest are in intra thyroid  location. It is mainly sporadic and more common in female with male to female ratio being 1:3.  Multi glandular adenomas are seen in familial syndromes and lithium induced PHPT.Conclusion:Parathyroid adenoma is a rare presentation in young adult. With correlation of clinical findings,  biochemical and radiological investigation and histopathological examination parathyroid  adenoma can be diagnosed easily.

Keywords

Parathyroid adenoma, Primary hyperparathyroidism (PHPT), Parathormone (PTH)