Retrospective Study of Seroprevalence of Transfusion Transmissible Infections Among Blood Donors in a Tertiary Care Centre in Thane District of Maharashtra

Indian Journal of Applied Basic Medical Sciences
Year: 2020, Volume: 22(B), Issue. (2)
First page: (159) Last page: (171)
Online ISSN: 2249-7935
Print ISSN: 0975-8917
doi:

Retrospective Study of Seroprevalence of Transfusion Transmissible Infections Among Blood Donors in a Tertiary Care Centre in Thane District of Maharashtra
Vaibhav Bari1, Shivkumar Kori2* , Milind Ubale3
1,2Associate Professor of pathology , Department of Pathology, Rajiv Gandhi Medical College, Kalwa, Thane, Maharashtra3Professor & Head, Department of Microbiology, Rajiv Gandhi Medical College, Kalwa, Thane, Maharashtra
Corresponding author email id: vbbari@gmail.com

Online Published on 02-July-2020

ABSTRACT

Background: Blood transfusion is an integral part of health care as well as one of the life saving procedure. But it carries risk of certain infections, especially viral, known as transfusion transmissible infections (TTIs). Aim: To study seroprevalence of TTIs (HIV, HBsAg, HCV, and syphilis & malaria) in a tertiary care centre in Thane district of Maharashtra. Study design: Hospital based retrospective observational study Methodology: The retrospective study was conducted by accumulating and analysing the data regarding TTIs from blood bank records. Total 20270 blood units were collected in 10 years period from January 2010 to December 2019. All blood units were screened by respective immunological methods. Results: On analysis of the data of all screened blood units, it was observed that 89 tested positive for HIV (0.44%), 463 were positive for HBsAg (2.28 %) & 115 were positive for HCV (0.56%). The seroprevalence for syphilis and malaria was 0.07% & 0.02% respectively. The overall seropositivity was 3.39%. The HBsAg seroprevalence was the highest among the blood donors. Conclusion: In order to avoid wastage of blood units, application of strict criteria for selection and deferral of donors with emphasis on TTIs along with mandatory Nucleic Acid Test (NAT) for screening of TTIs is required.

Keywords

Blood donors, Blood transfusions, Transfusion Transmissible Infections,

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