Prospective Study of Non Invasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Indian Journal of Applied Basic Medical Sciences
Year: 2020, Volume: 22(B), Issue. (2)
First page: (368) Last page: (377)
Online ISSN: 2249-7935
Print ISSN: 0975-8917
doi: 10.48165/ijabms.2020.22228

Prospective Study of Non Invasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Hemang Suthar1,  Sunita Solanki2*,  Keyur Panasara3
1Associate Professor of medicine, 2Assistant Professor of medicine, 3Second year medicine resident, Smt NHL Medical College,Elisbridge Ahmedabad pin 380006 India
Corresponding author email id:sunita.rahul1979@gmail.com

Online Published on 02-July-2020

ABSTRACT

Background: Patients with chronic obstructive pulmonary disease are also prone to exacerbation with progression of their disease, which often lead to hypercapnic respiratory failure. Noninvasive ventilation has shown to have good outcomes in terms of reduction in mortality, reduction in need for intubation and mechanical ventilation and decreased duration of stay in the hospital in patients with COPD Aims & objectives: To study the efficacy of Non Invasive Ventilation, to check demographic profile, to measure the serial arterial blood gas analysis and to monitor respiratory status in patients with acute exacerbation of chronic obstructive pulmonary disease. Material & methods: A total of 50 patients were included in this prospective cross-sectional study. Detail history, clinical examination was done. Arterial blood gas analysis and laboratory parameters were studied before and after non-invasive ventilation. Results: 86% of patients belonged to 46-75 years of age. 78% of patients were male. 78% of patients were addicted to tobacco in any form. Significant improvement was found in pH, pO2, pCO2 value in arterial blood gas analysis and SpO2 value after four hours of noninvasive ventilation. Conclusion: Noninvasive ventilation is well tolerated in patients with acute exacerbation of chronic obstructive pulmonary disease.

Keywords

Chronic obstructive pulmonary disease ,NIV