Role of Diffusion Weighted Magnetic Resonance Imaging in Brain Pathologies

Indian Journal of Applied Basic Medical Sciences
Year: 2020, Volume: 22(A), Issue. (1)
First page: (70) Last page: (85)
Online ISSN: 2249-7935
Print ISSN: 0975-8917

Role of Diffusion Weighted Magnetic Resonance Imaging in Brain Pathologies
Deepak Rajput 1,Drusty K. Majmudar 2,Amit G. Rathod3
1Associate Professor,2Assistant Professor, 3Second Year Resident Doctor 
Department of Radiology, AMC MET Medical college and LG hospital, Ahmedabad- 380008
Corresponding author email id

Online Published on 02-Jan-2020


Diffusion weighted imaging (DWI) has a wide range of applications in the evaluation of  brain pathologies. This study was conducted to correlate Diffusion weighted MR imaging features of  brain pathologies with other MRI sequences, to evaluate the role of DWI in brain pathologies. A  prospective, observational and cross section study was performed of 100 patients in 6-month  period. Patient with clinical suspicion of stroke, CNS infections, head injury, demyelination and  tumor were included. All MRI studies were done on Siemens magneto essenza 1.5 T MRI. Age wise  distribution, complaints, intra and extra axial location of tumor, presence and absence of restricted  diffusion and findings of various sequences of MRI were studied.  Methods: The present study was conducted in the Department of Radiology at AMC MET Medical  college and LG hospital. Participants after understanding the study protocol and procedure were  asked to give their written consent for the study.  Results: in our study maximum cases were observed from 5th to 6th decades. 91 cases were intra axial, 9 were extra-axial. 52% cases of stroke comprised of arterial infarct (39%), venous infarct (4%), HIE (3%), PRES (4%) and parenchyma haemorrhage (2%). 17% of cases were tumours which included  glioma, metastases, GBM and hemangiopericytoma. 5% case of cavernous haemangioma and 5%  cases of arachnoid cysts. 15% case of brain infections were included. All acute and subacute arterial  infarcts and all venous infarcts showed restriction on diffusion weighted images and chronic cases  did not show restriction. High grade gliomas, astrocytomas, and metastases showed diffusion  restriction.


DWI, Intracranial brain pathology, MRI (Magnetic resonance imaging), T2W (T2  weighted), FLAIR, ADC.