Cardiac & Pulmonary Complications Seen in Liver Cirrhosis-An Observational Study at a Tertiary Care Hospital

Indian Journal of Applied Basic Medical Sciences
Year: 2020, Volume: 22(A), Issue. (1)
First page: (118) Last page: (136)
Online ISSN: 2249-7935
Print ISSN: 0975-8917
doi:10.48165/ijabms.2020.22112

Online Published on 02-Jan-2020

ABSTRACT

Cardiac & Pulmonary Complications Seen in Liver Cirrhosis-An Observational  Study at a Tertiary Care Hospital 
Jyoti H. Vora1 ,Tehsim Memon2, Karan Keshawala3
Department of General Medicine, Smt NHL Municipal Medical College, Gujarat  University, Ahmedabad, Gujarat  
Corresponding author email id:

INTRODUCTION: Cirrhosis is a condition that is defined histopathologically and has a variety  of clinical manifestations and complications, some of which can be life-threatening. Patients  with cirrhosis and portal hypertension exhibit characteristic cardiovascular & pulmonary  hemodynamic changes. The cardiovascular complications include systolic dysfunction,  diastolic dysfunction & electrochemical abnormalities like prolonged QT interval in  Electrocardiogram (ECG), and Respiratory complications include Consolidation, Pleural  Effusion & Pulmonary Arterial Hypertension, which may be due to Hepatopulmonary or  Portopulmonary syndrome STUDY DESIGN: A two-year prospective observational study was conducted from July,2014  to June 2016 AIM: To study the different cardiac and pulmonary complications in the patients of Liver  Cirrhosis. MATERIALS & METHODS: A two-year prospective observational study was conducted from  July,2014 to June 2016 at a tertiary care hospital in Ahmedabad, Gujarat, India, including 30  patients (>12 years old), who were known cases of cirrhosis of liver as well as those newly  diagnosed with it, with cardiopulmonary complications, developed after liver cirrhosis, in  the absence of other etiological factors. Clinical profile with laboratory studies and  diagnostic tests were studied.  RESULTS: This study showed that cardiopulmonary complications in cirrhotic patients are  more frequently seen in males than females, which commonly manifest during third &  fourth decade. Dyspnoea is the most common symptom seen in the study. Among the  pulmonary complications, Pneumonia & Hydrothorax are more common compared to  hepatopulmonary & portopulmonary syndromes, and among cardiac complications,  Diastolic dysfunction is a major complication in such patients, which increases with  increasing severity of cirrhosis, as indicated by CP score. CONCLUSION: Among these patients, Cardiac and pulmonary complications have nearly the  same incidences.

Keywords

characteristic,cardiovascula ,pulmonary hemodynamic, Electrocardiogram , Hypertension