Histopathological Spectrum Of Granulomatous Dermatoses

Indian Journal of Applied Basic Medical Sciences
Year: 2019, Volume: 21(B), Issue. (2)
First page: (65) Last page: (75)
Online ISSN: 2249-7935
Print ISSN: 0975-8917

Histopathological Spectrum Of Granulomatous Dermatoses 
Swati Panchal1 , Falguni R Shah2*, Jigar Suthar3
1,3Resident, 2Professor, Department of Pathology AMC  MET Medical College & L.G.Hospital Maninagar, Ahmedabad 
Corresponding author email id: frshahpatho@gmail.com

Online Published on 02-Jul-2019


Granulomatous inflammation is a common histological pattern encountered in skin biopsies which pose a diagnostic challenge to pathologists because of overlapping histological features produced by various aetiological agents. Pathologists come across the lesion frequently and through knowledge of Granulomatous lesions are very much essential to discriminate them from other lesions, in the skin as they closely mimic each other. Incidence and prevalence of different types of granulomatous dermatitis depend on geographical Location. AIMS AND OBJECTIVES To know the types of different granulomatous dematoses, their prevalence and histopathological spectrum.
MATERIAL AND METHODA total of 1152 skin biopsies received from a period of January 2016 to October 2018 at Histopathology department of AMC MET Medical College, Ahmedabad. All specimens were fixed in 10% formalin and processed by routine paraffin embedding technique. All specimens were stained with Hematoxylin and eosin stain & some special stains like 5% AFB and 20% AFB were used as required. Slides were examined and histopathological diagnoses were given. RESULT A total o f 1152 skin biopsies received, out of which 80 cases were diagnosed as granulomatous dermatoses. Among 80 cases 54 (67.5%) were males and 26 (32.5%) were females. So ratio was 2.1:1 . The most common type was leprosy (52.50%) followed lesions consisting of lupus vulgaris(11.25%), Granuloma annulare (7.50%). Dermal granulomas were most common between age group of 21 to 30 years of age (38.75%). In leprosy , Borderline tubeculoid was the most common type (66.66%),followed by lepromatous leprosy (23.80%).CONCLUSION Histopathology is gold standard for diagnosis and categorization of Granulomatous skin lesions which will help in implicating health programs and management of individual cases.


Granulomatous dermatoses, histopathology, leprosy

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