Comparison Of Different Doses Of Clonidine As Adjuvant to Local Anesthetic Agent In Supraclavicular Block For Postoperative Analgesia

Indian Journal of Applied Basic Medical Sciences
Year: 2019, Volume: 21(B), Issue. (2)
First page: (154) Last page: (168)
Online ISSN: 2249-7935
Print ISSN: 0975-8917
doi:

Comparison Of Different Doses Of Clonidine As Adjuvant To Local Anesthetic  Agent In Supraclavicular Block For Postoperative Analgesia
Darshana Shah1, Manisha  Kapdi2*, Sumedh Prajapati3, Bansi Resident4, Avani  Resident5, Ronak6
1Associate Professor in Anaesthesia,2-5Resident AMC MET college, Ahmedabad
6Resident Dept of Anaesthesia, NHL Medical college and VS General Hospital  ELisbridge , Ahmedabad Pin 380006,Gujarat 
Corresponding author email id:manisha_ kapdi@yahoo.com 

Online Published on 02-Jul-2019

ABSTRACT

BACKGROUND: supraclavicular bracheal plexus block(SBB) is used worldwide,for upper limb surgeries various adjuvant used to improve quality of the Anaesthesia as well as for increased duration of postoperative analgesia. AIMS & OBJECTIVES:
:To access different dose of clonidine as adjuvant in SBB MATERIAL & METHODS:
50 patients of ASA grade I or II, scheduled for upper limb surgeries, were randomly divided in two groups (A & B) of 25 each. Supraclavicular brachial plexus block(SBB) performed with 20 ml lignocaine adrenaline 1.5%, 10 ml bupivacaine 0.5% and study drug in all patients. Group A received 75 µg clonidine in 1 ml saline. Group B received 150 µg clonidine in 1 ml saline. Onset and duration of sensory and motor blockade was noted. Patients were watched for intraoperative and postoperative side effects of drug, procedure related complications and hemodynamic alterations. Duration of postoperative analgesia was interpreted by VAS score and noted in terms of first rescue analgesic needed. OBSERVATIONS& RESULTS : Demographics were comparable in both the groups.1 time of onset for sensory block in Group B (6.04±0.93 min) was significantly lower than Group A (6.48±0.82 min). Mean duration of sensory block was longer in Group B (9.66±1.59 hr) as compared to Group A (7.10±0.32 hr). Mean onset time for motor block in Group B (11.24±1.01 min) was significantly lower than Group A (12.72±1.34 min). Mean duration of motor blockade was longer in Group B (7.22±0.69 hr) as compared to Group A (5.32±0.36 hr). Also, Duration of analgesia was significantly longer in Group B (11.7±1.61 hr) as compared to Group A (8.72±0.36 hr). Preoperative & postoperative cardiorespiratory stability achieved in each group.
No any significant incidence of intraoperative or postoperative complication was observed in any group. Conclusion: 150 mcg of clonidine is better adjuvant than 75 mcg for SBB.

Keywords

intraoperative, postoperative, blockade, drug

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